One of the big cartoon shows of the '80s would have to include Alvin & The Chipmunks. The series ran from 1983 to 1990- a pretty good run for a cartoon series. Of course, I would be remiss if I didn't mention the original cartoon that starred the Chipmunks, the 1961 series- The Alvin Show. And I've recently heard that the Chipmunks are due to have a new cartoon series in 2015 as well, this time using CGI-animation.
Unfortunately, this is a series that has not gotten season DVD sets released and it is uncertain if it ever will. (Most likely due to all the music used in the series.) However, thankfully, there have been numerous compilation releases of episodes on VHS and DVD. This thread is an attempt to catalogue those releases. I seem to recall someone asking me about this show on the forums here and that sparked my interest in reading up on this series again, though I've long been a fan of Alvin, Simon and Theodore and Dave Seville, of course.
For now, I have seen that Wikipedia has some excellent lists already posted, so I will direct readers to those. Over time, I may see about compacting the information available to a different format on this thread, but check out the posts here, here and here for now.
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